Reconstitution of Mdm2-Dependent Post-Translational Modifications of p53 in Yeast

p53 mediates cell cycle arrest or apoptosis in response to DNA damage. Its activity is subject to a tight regulation involving a multitude of post-translational modifications. The plethora of functional protein interactions of p53 at present precludes a clear understanding of regulatory principles i...

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Detalles Bibliográficos
Autores principales: Di Ventura, Barbara, Funaya, Charlotta, Antony, Claude, Knop, Michael, Serrano, Luis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200829/
https://www.ncbi.nlm.nih.gov/pubmed/18231594
http://dx.doi.org/10.1371/journal.pone.0001507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200829/
https://www.ncbi.nlm.nih.gov/pubmed/18231594
http://dx.doi.org/10.1371/journal.pone.0001507

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