Cargando…
Reconstitution of Mdm2-Dependent Post-Translational Modifications of p53 in Yeast
p53 mediates cell cycle arrest or apoptosis in response to DNA damage. Its activity is subject to a tight regulation involving a multitude of post-translational modifications. The plethora of functional protein interactions of p53 at present precludes a clear understanding of regulatory principles i...
Autores principales: | Di Ventura, Barbara, Funaya, Charlotta, Antony, Claude, Knop, Michael, Serrano, Luis |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200829/ https://www.ncbi.nlm.nih.gov/pubmed/18231594 http://dx.doi.org/10.1371/journal.pone.0001507 |
Ejemplares similares
-
Targeting Post-Translational Regulation of p53 in Colorectal Cancer by Exploiting Vulnerabilities in the p53-MDM2 Axis
por: Lai, Chunwei W., et al.
Publicado: (2022) -
Surf the Post-translational Modification Network of p53 Regulation
por: Gu, Bo, et al.
Publicado: (2012) -
MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation
por: Qi, Dong-Lai, et al.
Publicado: (2016) -
ESCRT machinery mediates selective microautophagy of endoplasmic reticulum in yeast
por: Schäfer, Jasmin A, et al.
Publicado: (2019) -
Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2
por: García‐Cano, Jesús, et al.
Publicado: (2019)