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Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome
BACKGROUND: Biomarker-based assessments of biological samples are widespread in clinical, pre-clinical, and epidemiological investigations. We previously developed serum metabolomic profiles assessed by HPLC-separations coupled with coulometric array detection that can accurately identify ad libitum...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203971/ https://www.ncbi.nlm.nih.gov/pubmed/17997839 http://dx.doi.org/10.1186/1472-6890-7-9 |