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Membrane binding of the neuronal calcium sensor recoverin – modulatory role of the charged carboxy-terminus

BACKGROUND: The Ca(2+)-binding protein recoverin operates as a Ca(2+)-sensor in vertebrate photoreceptor cells. It undergoes a so-called Ca(2+)-myristoyl switch when cytoplasmic Ca(2+)-concentrations fluctuate in the cell. Its covalently attached myristoyl-group is exposed at high Ca(2+)-concentrati...

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Detalles Bibliográficos
Autores principales: Senin, Ivan I, Churumova, Valeriya A, Philippov, Pavel P, Koch, Karl-Wilhelm
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203989/
https://www.ncbi.nlm.nih.gov/pubmed/18034895
http://dx.doi.org/10.1186/1471-2091-8-24