K(+) Channel Regulator KCR1 Suppresses Heart Rhythm by Modulating the Pacemaker Current I(f)

Hyperpolarization-activated, cyclic nucleotide sensitive (HCN) channels underlie the pacemaker current I(f), which plays an essential role in spontaneous cardiac activity. HCN channel subunits (HCN1-4) are believed to be modulated by additional regulatory proteins, which still have to be identified....

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Detalles Bibliográficos
Autores principales: Michels, Guido, Er, Fikret, Khan, Ismail F., Endres-Becker, Jeannette, Brandt, Mathias C., Gassanov, Natig, Johns, David C., Hoppe, Uta C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2204056/
https://www.ncbi.nlm.nih.gov/pubmed/18231597
http://dx.doi.org/10.1371/journal.pone.0001511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2204056/
https://www.ncbi.nlm.nih.gov/pubmed/18231597
http://dx.doi.org/10.1371/journal.pone.0001511

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