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K(+) Channel Regulator KCR1 Suppresses Heart Rhythm by Modulating the Pacemaker Current I(f)
Hyperpolarization-activated, cyclic nucleotide sensitive (HCN) channels underlie the pacemaker current I(f), which plays an essential role in spontaneous cardiac activity. HCN channel subunits (HCN1-4) are believed to be modulated by additional regulatory proteins, which still have to be identified....
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2204056/ https://www.ncbi.nlm.nih.gov/pubmed/18231597 http://dx.doi.org/10.1371/journal.pone.0001511 |