Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype

BACKGROUND: Genetic instability is a hallmark of tumours and preneoplastic lesions. The predominant form of genome instability in human cancer is chromosome instability (CIN). CIN is characterized by chromosomal aberrations, gains or losses of whole chromosomes (aneuploidy), and it is often associat...

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Detalles Bibliográficos
Autores principales: Lentini, Laura, Amato, Angela, Schillaci, Tiziana, Di Leonardo, Aldo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206046/
https://www.ncbi.nlm.nih.gov/pubmed/17999753
http://dx.doi.org/10.1186/1471-2407-7-212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206046/
https://www.ncbi.nlm.nih.gov/pubmed/17999753
http://dx.doi.org/10.1186/1471-2407-7-212

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