A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays

BACKGROUND: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlying events leading to cancer. Genomic copy-numbers are today routinely derived from SNP array data, but the proposed algor...

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Detalles Bibliográficos
Autores principales: Lamy, Philippe, Andersen, Claus L, Dyrskjot, Lars, Torring, Niels, Wiuf, Carsten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206057/
https://www.ncbi.nlm.nih.gov/pubmed/17996079
http://dx.doi.org/10.1186/1471-2105-8-434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206057/
https://www.ncbi.nlm.nih.gov/pubmed/17996079
http://dx.doi.org/10.1186/1471-2105-8-434

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