Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

Indoleamine 2,3-dioxygenase (IDO) is one of the initial and rate-limiting enzymes involved in the catabolism of the essential amino acid tryptophan. In cultured cells, the induction of IDO leads to depletion of tryptophan and tryptophan starvation. Recent studies suggest that modulation of tryptopha...

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Detalles Bibliográficos
Autores principales: Szántó, Sándor, Koreny, Tamás, Mikecz, Katalin, Glant, Tibor T, Szekanecz, Zoltán, Varga, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206348/
https://www.ncbi.nlm.nih.gov/pubmed/17511858
http://dx.doi.org/10.1186/ar2205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206348/
https://www.ncbi.nlm.nih.gov/pubmed/17511858
http://dx.doi.org/10.1186/ar2205

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