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B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue

Primary Sjögren's syndrome (pSS) is an autoimmune disorder characterized by specific pathological features. A hallmark of pSS is B-cell hyperactivity as manifested by the production of autoantibodies, hypergammaglobulinemia, formation of ectopic lymphoid structures within the inflamed tissues,...

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Detalles Bibliográficos
Autores principales: Hansen, Arne, Lipsky, Peter E, Dörner, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206371/
https://www.ncbi.nlm.nih.gov/pubmed/17697366
http://dx.doi.org/10.1186/ar2210