The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells

INTRODUCTION: There is growing evidence that the Wilms' tumor 1 suppressor gene (WT1) behaves as an oncogene in some forms of breast cancer. Previous studies have demonstrated that the N-terminal domain of WT1 can act as a dominant negative through self-association. In the studies presented her...

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Detalles Bibliográficos
Autores principales: Han, Youqi, San-Marina, Serban, Yang, Lin, Khoury, Haytham, Minden, Mark D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206716/
https://www.ncbi.nlm.nih.gov/pubmed/17634147
http://dx.doi.org/10.1186/bcr1743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206716/
https://www.ncbi.nlm.nih.gov/pubmed/17634147
http://dx.doi.org/10.1186/bcr1743

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