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Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCε and JAK2 in RAW macrophages

BACKGROUND: Nuclear factor kappa B (NF-κB) has been shown to play an important role in regulating the expression of many genes involved in cell survival, immunity and in the inflammatory processes. NF-κB activation upregulates inducible nitric oxide synthase leading to enhanced nitric oxide producti...

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Detalles Bibliográficos
Autores principales: Jones, Edward, Adcock, Ian M, Ahmed, Bushra Y, Punchard, Neville A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211292/
https://www.ncbi.nlm.nih.gov/pubmed/18036230
http://dx.doi.org/10.1186/1476-9255-4-23