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The Alzheimer's disease β-secretase enzyme, BACE1

The pathogenesis of Alzheimer's disease is highly complex. While several pathologies characterize this disease, amyloid plaques, composed of the β-amyloid peptide are hallmark neuropathological lesions in Alzheimer's disease brain. Indeed, a wealth of evidence suggests that β-amyloid is ce...

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Detalles Bibliográficos
Autores principales: Cole, Sarah L, Vassar, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211305/
https://www.ncbi.nlm.nih.gov/pubmed/18005427
http://dx.doi.org/10.1186/1750-1326-2-22