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The Alzheimer's disease β-secretase enzyme, BACE1
The pathogenesis of Alzheimer's disease is highly complex. While several pathologies characterize this disease, amyloid plaques, composed of the β-amyloid peptide are hallmark neuropathological lesions in Alzheimer's disease brain. Indeed, a wealth of evidence suggests that β-amyloid is ce...
Autores principales: | Cole, Sarah L, Vassar, Robert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211305/ https://www.ncbi.nlm.nih.gov/pubmed/18005427 http://dx.doi.org/10.1186/1750-1326-2-22 |
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