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Anti-Human Tissue Factor Antibody Ameliorated Intestinal Ischemia Reperfusion-Induced Acute Lung Injury in Human Tissue Factor Knock-In Mice

BACKGROUND: Interaction between the coagulation and inflammation systems plays an important role in the development of acute respiratory distress syndrome (ARDS). Anti-coagulation is an attractive option for ARDS treatment, and this has promoted development of new antibodies. However, preclinical tr...

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Detalles Bibliográficos
Autores principales: He, Xiaolin, Han, Bing, Mura, Marco, Li, Li, Cypel, Marcelo, Soderman, Avery, Picha, Kristen, Yang, Jing, Liu, Mingyao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211395/
https://www.ncbi.nlm.nih.gov/pubmed/18231608
http://dx.doi.org/10.1371/journal.pone.0001527