A Novel ZAP-70 Dependent FRET Based Biosensor Reveals Kinase Activity at both the Immunological Synapse and the Antisynapse

Many hypotheses attempting to explain the speed and sensitivity with which a T-cell discriminates the antigens it encounters include a notion of relative spatial and temporal control of particular biochemical steps involved in the process. An essential step in T-cell receptor (TCR) mediated signalli...

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Detalles Bibliográficos
Autores principales: Randriamampita, Clotilde, Mouchacca, Pierre, Malissen, Bernard, Marguet, Didier, Trautmann, Alain, Lellouch, Annemarie Coffman
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211399/
https://www.ncbi.nlm.nih.gov/pubmed/18231606
http://dx.doi.org/10.1371/journal.pone.0001521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211399/
https://www.ncbi.nlm.nih.gov/pubmed/18231606
http://dx.doi.org/10.1371/journal.pone.0001521

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