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Lineage Diversion of T Cell Receptor Transgenic Thymocytes Revealed by Lineage Fate Mapping
BACKGROUND: The binding of the T cell receptor (TCR) to major histocompatibility complex (MHC) molecules in the thymus determines fates of TCRαβ lymphocytes that subsequently home to secondary lymphoid tissue. TCR transgenic models have been used to study thymic selection and lineage commitment. Mos...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211402/ https://www.ncbi.nlm.nih.gov/pubmed/18231598 http://dx.doi.org/10.1371/journal.pone.0001512 |