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Evolution and Diversity of Clonal Bacteria: The Paradigm of Mycobacterium tuberculosis

BACKGROUND: Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task. PRINCIPAL FINDINGS: We found that single-nucleotide polymorphism (SNP)...

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Detalles Bibliográficos
Autores principales: Dos Vultos, Tiago, Mestre, Olga, Rauzier, Jean, Golec, Marcin, Rastogi, Nalin, Rasolofo, Voahangy, Tonjum, Tone, Sola, Christophe, Matic, Ivan, Gicquel, Brigitte
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211405/
https://www.ncbi.nlm.nih.gov/pubmed/18253486
http://dx.doi.org/10.1371/journal.pone.0001538