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Evolution and Diversity of Clonal Bacteria: The Paradigm of Mycobacterium tuberculosis
BACKGROUND: Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task. PRINCIPAL FINDINGS: We found that single-nucleotide polymorphism (SNP)...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211405/ https://www.ncbi.nlm.nih.gov/pubmed/18253486 http://dx.doi.org/10.1371/journal.pone.0001538 |