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Differential intracellular distribution of DNA complexed with polyethylenimine (PEI) and PEI-polyarginine PTD influences exogenous gene expression within live COS-7 cells

BACKGROUND: Polyethylenimine (PEI) is one of the most efficient and versatile non-viral vectors available for gene delivery. Despite many advantages over viral vectors, PEI is still limited by lower transfection efficiency compared to its viral counterparts. Considerable investigation is devoted to...

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Detalles Bibliográficos
Autores principales: Doyle, Stephen R, Chan, Chee Kai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211466/
https://www.ncbi.nlm.nih.gov/pubmed/18036259
http://dx.doi.org/10.1186/1479-0556-5-11