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In Silico Detection of Sequence Variations Modifying Transcriptional Regulation

Identification of functional genetic variation associated with increased susceptibility to complex diseases can elucidate genes and underlying biochemical mechanisms linked to disease onset and progression. For genes linked to genetic diseases, most identified causal mutations alter an encoded prote...

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Detalles Bibliográficos
Autores principales: Andersen, Malin C, Engström, Pär G, Lithwick, Stuart, Arenillas, David, Eriksson, Per, Lenhard, Boris, Wasserman, Wyeth W, Odeberg, Jacob
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211530/
https://www.ncbi.nlm.nih.gov/pubmed/18208319
http://dx.doi.org/10.1371/journal.pcbi.0040005