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Co-Regulation of Metabolic Genes Is Better Explained by Flux Coupling Than by Network Distance

To what extent can modes of gene regulation be explained by systems-level properties of metabolic networks? Prior studies on co-regulation of metabolic genes have mainly focused on graph-theoretical features of metabolic networks and demonstrated a decreasing level of co-expression with increasing n...

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Detalles Bibliográficos
Autores principales: Notebaart, Richard A, Teusink, Bas, Siezen, Roland J, Papp, Balázs
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211535/
https://www.ncbi.nlm.nih.gov/pubmed/18225949
http://dx.doi.org/10.1371/journal.pcbi.0040026