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Generation of shRNAs from randomized oligonucleotides

Suppression of gene expression by small interfering RNA (siRNA) has proved to be a gene-specific and cost effective alternative to other gene suppression technologies. Short hairpin RNAs (shRNAs) generated from the vector-based expression are believed to be processed into functional siRNAs in vivo,...

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Detalles Bibliográficos
Autores principales: Wu, Hailong, Dinh, Anh, Mo, Yin-Yuan
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211575/
https://www.ncbi.nlm.nih.gov/pubmed/18213360
http://dx.doi.org/10.1251/bpo129