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Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages

BACKGROUND: HIV-1 Vpr is a dynamic protein that primarily localizes in the nucleus, but a significant fraction is concentrated at the nuclear envelope (NE), supporting an interaction between Vpr and components of the nuclear pore complex, including the nucleoporin hCG1. In the present study, we have...

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Detalles Bibliográficos
Autores principales: Jacquot, Guillaume, Le Rouzic, Erwann, David, Annie, Mazzolini, Julie, Bouchet, Jérôme, Bouaziz, Serge, Niedergang, Florence, Pancino, Gianfranco, Benichou, Serge
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211753/
https://www.ncbi.nlm.nih.gov/pubmed/18039376
http://dx.doi.org/10.1186/1742-4690-4-84