Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-specific Genes Colocalized in Chromosomal Clusters

Promiscuous expression of tissue-specific self-antigens in the thymus imposes T cell tolerance and protects from autoimmune diseases, as shown in animal studies. Analysis of promiscuous gene expression in purified stromal cells of the human thymus at the single and global gene level documents the sp...

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Detalles Bibliográficos
Autores principales: Gotter, Jörn, Brors, Benedikt, Hergenhahn, Manfred, Kyewski, Bruno
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211762/
https://www.ncbi.nlm.nih.gov/pubmed/14734521
http://dx.doi.org/10.1084/jem.20031677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211762/
https://www.ncbi.nlm.nih.gov/pubmed/14734521
http://dx.doi.org/10.1084/jem.20031677

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