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Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptide

The products of the human leukocyte antigen subtypes HLA-B*2705 and HLA-B*2709 differ only in residue 116 (Asp vs. His) within the peptide binding groove but are differentially associated with the autoimmune disease ankylosing spondylitis (AS); HLA-B*2705 occurs in AS-patients, whereas HLA-B*2709 do...

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Detalles Bibliográficos
Autores principales: Hülsmeyer, Martin, Fiorillo, Maria Teresa, Bettosini, Francesca, Sorrentino, Rosa, Saenger, Wolfram, Ziegler, Andreas, Uchanska-Ziegler, Barbara
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211767/
https://www.ncbi.nlm.nih.gov/pubmed/14734527
http://dx.doi.org/10.1084/jem.20031690