Activation of Arterial Wall Dendritic Cells and Breakdown of Self-tolerance in Giant Cell Arteritis

Giant cell arteritis (GCA) is a granulomatous and occlusive vasculitis that causes blindness, stroke, and aortic aneurysm. CD4(+) T cells are selectively activated in the adventitia of affected arteries. In human GCA artery–severe combined immunodeficiency (SCID) mouse chimeras, depletion of CD83(+)...

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Detalles Bibliográficos
Autores principales: Ma-Krupa, Wei, Jeon, Myung-Shin, Spoerl, Silvia, Tedder, Thomas F., Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211768/
https://www.ncbi.nlm.nih.gov/pubmed/14734523
http://dx.doi.org/10.1084/jem.20030850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211768/
https://www.ncbi.nlm.nih.gov/pubmed/14734523
http://dx.doi.org/10.1084/jem.20030850

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