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Activation of Arterial Wall Dendritic Cells and Breakdown of Self-tolerance in Giant Cell Arteritis
Giant cell arteritis (GCA) is a granulomatous and occlusive vasculitis that causes blindness, stroke, and aortic aneurysm. CD4(+) T cells are selectively activated in the adventitia of affected arteries. In human GCA artery–severe combined immunodeficiency (SCID) mouse chimeras, depletion of CD83(+)...
Autores principales: | Ma-Krupa, Wei, Jeon, Myung-Shin, Spoerl, Silvia, Tedder, Thomas F., Goronzy, Jörg J., Weyand, Cornelia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211768/ https://www.ncbi.nlm.nih.gov/pubmed/14734523 http://dx.doi.org/10.1084/jem.20030850 |
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