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In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes
The low number of CD4(+) CD25(+) regulatory T cells (T(regs)), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic population to treat autoimmunity and transplant rejection. In this study, we describe a robust method to expand antig...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211775/ https://www.ncbi.nlm.nih.gov/pubmed/15184499 http://dx.doi.org/10.1084/jem.20040139 |