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Differential Regulation of TCR-mediated Gene Transcription by Vav Family Members

Although all three Vav family members are expressed in T lymphocytes, the role that Vav3 plays in T cell activation is poorly defined. Here we show that, like Vav1, Vav3 undergoes rapid tyrosine phosphorylation after T cell receptor (TCR) cross-linkage and interacts with the adaptor molecules SLP76...

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Detalles Bibliográficos
Autores principales: Zakaria, Shaheen, Gomez, Timothy S., Savoy, Doris N., McAdam, Simon, Turner, Martin, Abraham, Robert T., Billadeau, Daniel D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211790/
https://www.ncbi.nlm.nih.gov/pubmed/14757747
http://dx.doi.org/10.1084/jem.20031228