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Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4(+) Regulatory T Cells

Regulatory T cells (Tregs) fulfill a central role in immune regulation. We reported previously that the integrin α(E)β(7) discriminates distinct subsets of murine CD4(+) regulatory T cells. Use of this marker has now helped to unravel a fundamental dichotomy among regulatory T cells. α(E) (−)CD25(+)...

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Detalles Bibliográficos
Autores principales: Huehn, Jochen, Siegmund, Kerstin, Lehmann, Joachim C.U., Siewert, Christiane, Haubold, Uta, Feuerer, Markus, Debes, Gudrun F., Lauber, Joerg, Frey, Oliver, Przybylski, Grzegorz K., Niesner, Uwe, de la Rosa, Maurus, Schmidt, Christian A., Bräuer, Rolf, Buer, Jan, Scheffold, Alexander, Hamann, Alf
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211798/
https://www.ncbi.nlm.nih.gov/pubmed/14757740
http://dx.doi.org/10.1084/jem.20031562