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The Metallo-β-Lactamase/β-CASP Domain of Artemis Constitutes the Catalytic Core for V(D)J Recombination

The V(D)J recombination/DNA repair factor Artemis belongs to the metallo-β-lactamase (β-Lact) superfamily of enzymes. Three regions can be defined within the Artemis protein sequence: (a) the β-Lact homology domain, to which is appended (b) the β-CASP region, specific of members of the β-Lact superf...

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Detalles Bibliográficos
Autores principales: Poinsignon, Catherine, Moshous, Despina, Callebaut, Isabelle, de Chasseval, Régina, Villey, Isabelle, de Villartay, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211804/
https://www.ncbi.nlm.nih.gov/pubmed/14744996
http://dx.doi.org/10.1084/jem.20031142