Cargando…

The CD8 Population in CD4-deficient Mice Is Heavily Contaminated with MHC Class II–restricted T Cells

In experiments to study the impact of deficiency in CD4(+) T cell help on the magnitude of CD8(+) cytotoxic T cell response to pathogens, it was noted that in CD4 gene knockout mice, the CD8 population made significant responses to several nominally major histocompatibility complex (MHC) class II–re...

Descripción completa

Detalles Bibliográficos
Autores principales: Tyznik, Aaron J., Sun, Joseph C., Bevan, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211827/
https://www.ncbi.nlm.nih.gov/pubmed/14769854
http://dx.doi.org/10.1084/jem.20031961