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The CD8 Population in CD4-deficient Mice Is Heavily Contaminated with MHC Class II–restricted T Cells
In experiments to study the impact of deficiency in CD4(+) T cell help on the magnitude of CD8(+) cytotoxic T cell response to pathogens, it was noted that in CD4 gene knockout mice, the CD8 population made significant responses to several nominally major histocompatibility complex (MHC) class II–re...
Autores principales: | Tyznik, Aaron J., Sun, Joseph C., Bevan, Michael J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211827/ https://www.ncbi.nlm.nih.gov/pubmed/14769854 http://dx.doi.org/10.1084/jem.20031961 |
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