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p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils

Neutrophil apoptosis occurs both in the bloodstream and in the tissue and is considered essential for the resolution of an inflammatory process. Here, we show that p38–mitogen-activated protein kinase (MAPK) associates to caspase-8 and caspase-3 during neutrophil apoptosis and that p38-MAPK activity...

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Detalles Bibliográficos
Autores principales: Alvarado-Kristensson, Maria, Melander, Fredrik, Leandersson, Karin, Rönnstrand, Lars, Wernstedt, Christer, Andersson, Tommy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211830/
https://www.ncbi.nlm.nih.gov/pubmed/14970175
http://dx.doi.org/10.1084/jem.20031771