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The Cytomegalovirus m155 Gene Product Subverts Natural Killer Cell Antiviral Protection by Disruption of H60–NKG2D Interactions

Natural killer (NK) cells are an important early mediator of host immunity to murine cytomegalovirus (MCMV) infection. However, MCMV has evolved mechanisms to elude recognition and clearance by NK cells. We have identified an MCMV immune evasion protein that impairs NKG2D-mediated NK cell antiviral...

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Detalles Bibliográficos
Autores principales: Lodoen, Melissa B., Abenes, Gerardo, Umamoto, Sean, Houchins, Jeffrey P., Liu, Fenyong, Lanier, Lewis L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211837/
https://www.ncbi.nlm.nih.gov/pubmed/15477345
http://dx.doi.org/10.1084/jem.20040583