Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation

Intrathymic expression of tissue-specific antigens (TSAs) by medullary thymic epithelial cells (Mtecs) leads to deletion of autoreactive T cells. However, because Mtecs are known to be poor antigen-presenting cells (APCs) for tolerance to ubiquitous antigens, and very few Mtecs express a given TSA,...

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Detalles Bibliográficos
Autores principales: Gallegos, Alena M., Bevan, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211843/
https://www.ncbi.nlm.nih.gov/pubmed/15492126
http://dx.doi.org/10.1084/jem.20041457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211843/
https://www.ncbi.nlm.nih.gov/pubmed/15492126
http://dx.doi.org/10.1084/jem.20041457

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