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Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation

Intrathymic expression of tissue-specific antigens (TSAs) by medullary thymic epithelial cells (Mtecs) leads to deletion of autoreactive T cells. However, because Mtecs are known to be poor antigen-presenting cells (APCs) for tolerance to ubiquitous antigens, and very few Mtecs express a given TSA,...

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Detalles Bibliográficos
Autores principales:	Gallegos, Alena M., Bevan, Michael J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211843/ https://www.ncbi.nlm.nih.gov/pubmed/15492126 http://dx.doi.org/10.1084/jem.20041457

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