Positive and Negative Regulation of FcɛRI-Mediated Signaling by the Adaptor Protein LAB/NTAL

Linker for activation of B cells (LAB, also called NTAL; a product of wbscr5 gene) is a newly identified transmembrane adaptor protein that is expressed in B cells, NK cells, and mast cells. Upon BCR activation, LAB is phosphorylated and interacts with Grb2. LAB is capable of rescuing thymocyte deve...

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Detalles Bibliográficos
Autores principales: Zhu, Minghua, Liu, Yan, Koonpaew, Surapong, Granillo, Olivia, Zhang, Weiguo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211849/
https://www.ncbi.nlm.nih.gov/pubmed/15477350
http://dx.doi.org/10.1084/jem.20041223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211849/
https://www.ncbi.nlm.nih.gov/pubmed/15477350
http://dx.doi.org/10.1084/jem.20041223

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