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Positive and Negative Regulation of FcɛRI-Mediated Signaling by the Adaptor Protein LAB/NTAL
Linker for activation of B cells (LAB, also called NTAL; a product of wbscr5 gene) is a newly identified transmembrane adaptor protein that is expressed in B cells, NK cells, and mast cells. Upon BCR activation, LAB is phosphorylated and interacts with Grb2. LAB is capable of rescuing thymocyte deve...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211849/ https://www.ncbi.nlm.nih.gov/pubmed/15477350 http://dx.doi.org/10.1084/jem.20041223 |