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Helicobacter pylori Modulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN

The human gastric pathogen Helicobacter pylori spontaneously switches lipopolysaccharide (LPS) Lewis (Le) antigens on and off (phase-variable expression), but the biological significance of this is unclear. Here, we report that Le(+) H. pylori variants are able to bind to the C-type lectin DC-SIGN a...

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Detalles Bibliográficos
Autores principales: Bergman, Mathijs P., Engering, Anneke, Smits, Hermelijn H., van Vliet, Sandra J., van Bodegraven, Ad A., Wirth, Hans-Peter, Kapsenberg, Martien L., Vandenbroucke-Grauls, Christina M.J.E., van Kooyk, Yvette, Appelmelk, Ben J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211851/
https://www.ncbi.nlm.nih.gov/pubmed/15492123
http://dx.doi.org/10.1084/jem.20041061