ATM Is Required for Efficient Recombination between Immunoglobulin Switch Regions

Ataxia telangiectasia mutated (ATM) kinase is critical for initiating the signaling pathways that lead to cell cycle checkpoints and DNA double strand break repair. In the absence of ATM, humans and mice show a primary immunodeficiency that includes low serum antibody titers, but the role of ATM in...

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Detalles Bibliográficos
Autores principales: Reina-San-Martin, Bernardo, Chen, Hua Tang, Nussenzweig, André, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211855/
https://www.ncbi.nlm.nih.gov/pubmed/15520243
http://dx.doi.org/10.1084/jem.20041162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211855/
https://www.ncbi.nlm.nih.gov/pubmed/15520243
http://dx.doi.org/10.1084/jem.20041162

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