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Inhibition of Phosphatidylserine Recognition Heightens the Immunogenicity of Irradiated Lymphoma Cells In Vivo

Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor. Annexin V (AxV) binds with high affinity to phosphatidylserine on the surface of apoptotic...

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Detalles Bibliográficos
Autores principales: Bondanza, Attilio, Zimmermann, Valérie S., Rovere-Querini, Patrizia, Turnay, Javier, Dumitriu, Ingrid E., Stach, Christian M., Voll, Reinhard E., Gaipl, Udo S., Bertling, Wolf, Pöschl, Ernst, Kalden, Joachim R., Manfredi, Angelo A., Herrmann, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211859/
https://www.ncbi.nlm.nih.gov/pubmed/15504819
http://dx.doi.org/10.1084/jem.20040327