Loss of Bim Allows Precursor B Cell Survival But Not Precursor B Cell Differentiation in the Absence of Interleukin 7

Interleukin (IL)-7 is a stromal cell–derived cytokine required for the survival, proliferation, and differentiation of B cell precursors. Members of the Bcl-2 family of proteins are known to have profound effects on lymphocyte survival, but not lymphocyte differentiation. To distinguish the relative...

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Detalles Bibliográficos
Autores principales: Oliver, Paula M., Wang, Michael, Zhu, Yanan, White, Janice, Kappler, John, Marrack, Philippa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211863/
https://www.ncbi.nlm.nih.gov/pubmed/15520248
http://dx.doi.org/10.1084/jem.20041129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211863/
https://www.ncbi.nlm.nih.gov/pubmed/15520248
http://dx.doi.org/10.1084/jem.20041129

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