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Reprogramming of Virus-specific T Cells into Leukemia-reactive T Cells Using T Cell Receptor Gene Transfer

T cells directed against minor histocompatibility antigens (mHags) might be responsible for eradication of hematological malignancies after allogeneic stem cell transplantation. We investigated whether transfer of T cell receptors (TCRs) directed against mHags, exclusively expressed on hematopoietic...

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Detalles Bibliográficos
Autores principales: Heemskerk, Mirjam H.M., Hoogeboom, Manja, Hagedoorn, Renate, Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211874/
https://www.ncbi.nlm.nih.gov/pubmed/15051765
http://dx.doi.org/10.1084/jem.20031110