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Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8(+) T Cells

CD8(+) T cells play a central role in the resolution and containment of viral infections. A key effector function of CD8(+) T cells is their cytolytic activity toward infected cells. Here, we studied the regulation of cytolytic activity in naive, effector, and central versus effector memory CD8(+) T...

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Detalles Bibliográficos
Autores principales: Wolint, Petra, Betts, Michael R., Koup, Richard A., Oxenius, Annette
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211884/
https://www.ncbi.nlm.nih.gov/pubmed/15051762
http://dx.doi.org/10.1084/jem.20031799