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Impaired Clearance of Apoptotic Cells Promotes Synergy between Atherogenesis and Autoimmune Disease
To clarify the link between autoimmune disease and hypercholesterolemia, we created the gld.apoE (−/−) mouse as a model of accelerated atherosclerosis. Atherosclerotic lesion area was significantly increased in gld.apoE (−/−) mice compared with apoE (−/−) mice. gld.apoE (−/−) mice also displayed inc...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211887/ https://www.ncbi.nlm.nih.gov/pubmed/15096538 http://dx.doi.org/10.1084/jem.20031557 |