Cargando…

Impaired Clearance of Apoptotic Cells Promotes Synergy between Atherogenesis and Autoimmune Disease

To clarify the link between autoimmune disease and hypercholesterolemia, we created the gld.apoE (−/−) mouse as a model of accelerated atherosclerosis. Atherosclerotic lesion area was significantly increased in gld.apoE (−/−) mice compared with apoE (−/−) mice. gld.apoE (−/−) mice also displayed inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Aprahamian, Tamar, Rifkin, Ian, Bonegio, Ramon, Hugel, Bénédicte, Freyssinet, Jean-Marie, Sato, Kaori, Castellot, John J., Walsh, Kenneth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211887/
https://www.ncbi.nlm.nih.gov/pubmed/15096538
http://dx.doi.org/10.1084/jem.20031557