Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A

Previous studies have indicated that the E2A gene products are required to initiate B lineage development. Here, we demonstrate that E2A(+/−) B cells that express an autoreactive B cell receptor fail to mature due in part to an inability to activate secondary immunoglobulin (Ig) light chain gene rea...

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Detalles Bibliográficos
Autores principales: Quong, Melanie W., Martensson, Annica, Langerak, Anton W., Rivera, Richard R., Nemazee, David, Murre, Cornelis
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211894/
https://www.ncbi.nlm.nih.gov/pubmed/15078898
http://dx.doi.org/10.1084/jem.20031180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211894/
https://www.ncbi.nlm.nih.gov/pubmed/15078898
http://dx.doi.org/10.1084/jem.20031180

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