Cargando…

DC-SIGN–mediated Infectious Synapse Formation Enhances X4 HIV-1 Transmission from Dendritic Cells to T Cells

Dendritic cells (DCs) are essential for the early events of human immunodeficiency virus (HIV) infection. Model systems of HIV sexual transmission have shown that DCs expressing the DC-specific C-type lectin DC-SIGN capture and internalize HIV at mucosal surfaces and efficiently transfer HIV to CD4(...

Descripción completa

Detalles Bibliográficos
Autores principales: Arrighi, Jean-François, Pion, Marjorie, Garcia, Eduardo, Escola, Jean-Michel, van Kooyk, Yvette, Geijtenbeek, Teunis B., Piguet, Vincent
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211914/
https://www.ncbi.nlm.nih.gov/pubmed/15545354
http://dx.doi.org/10.1084/jem.20041356