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DC-SIGN–mediated Infectious Synapse Formation Enhances X4 HIV-1 Transmission from Dendritic Cells to T Cells
Dendritic cells (DCs) are essential for the early events of human immunodeficiency virus (HIV) infection. Model systems of HIV sexual transmission have shown that DCs expressing the DC-specific C-type lectin DC-SIGN capture and internalize HIV at mucosal surfaces and efficiently transfer HIV to CD4(...
Autores principales: | Arrighi, Jean-François, Pion, Marjorie, Garcia, Eduardo, Escola, Jean-Michel, van Kooyk, Yvette, Geijtenbeek, Teunis B., Piguet, Vincent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211914/ https://www.ncbi.nlm.nih.gov/pubmed/15545354 http://dx.doi.org/10.1084/jem.20041356 |
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